Japanese Encephalitis (JE) is a serious viral infection that causes inflammation of the brain. It is spread by mosquitoes found in parts of Asia and the Western Pacific. Although rare in travellers, the infection can cause permanent neurological damage or be fatal.
The risk is highest in rural areas where rice fields, marshes and pig farming are common — but cases have also been reported on the outskirts of cities.
To check the risk in your specific destination, visit NaTHNaC:
https://travelhealthpro.org.uk/factsheet/31/japanese-encephalitis
Northfields Travel Clinic, based at Bramley Pharmacy, provides the Ixiaro® Japanese Encephalitis vaccine for adults and children.
JE is transmitted by Culex mosquitoes that:
Feed mainly from dusk to dawn
Thrive in rural, agricultural and wetland areas
Breed in rice paddies, floodwater and irrigation systems
Are common in areas with pig farming (pigs are amplifying hosts)
JE occurs in:
South Asia (India, Nepal, Sri Lanka)
Southeast Asia (Thailand, Vietnam, Cambodia, Laos, Myanmar, Indonesia)
China & Taiwan
Japan
Papua New Guinea
Pacific islands
Urban transmission is uncommon, but mosquitoes can still be found in some city outskirts.
The overall risk for short-term travellers is very low — estimated at less than 1 case per 1 million travellers.
However, risk increases if you:
Spend extended periods in rural or agricultural settings
Visit during the monsoon or peak transmission seasons
Go trekking, cycling, backpacking or camping
Engage in outdoor evening or night-time activities
Stay with local families in rural areas
Work in labs handling JE virus
Even short trips can carry risk if they involve significant rural exposure.
Most infections cause no symptoms.
In symptomatic cases, early symptoms include:
Fever
Headache
Tiredness
Nausea or vomiting
Severe illness can progress to:
Confusion
Seizures
Coma
Paralysis
Hospitalised cases have a high mortality rate (up to 30%)
Up to half of survivors experience long-term neurological complications
There is no specific antiviral treatment
Even with vaccination, travellers should practise mosquito bite avoidance between dusk and dawn:
Use 30–50% DEET or similar repellents
Wear long sleeves and trousers in the evenings
Sleep in screened or air-conditioned rooms
Use bed nets where needed
Avoid staying near rice fields, marshland or pig farms
Keep doors and windows closed at night
These precautions also protect against malaria and dengue in overlapping regions.
We provide Ixiaro®, the licensed inactivated JE vaccine used across Europe.
Brand: Ixiaro®
Doses: 2-dose primary course
Price: £140 per dose
Age suitability: From 2 months old
Protection: Begins ~7 days after the second dose
Booster: Recommended after 12–24 months if ongoing risk
Dose 1: Day 0
Dose 2: 28 days later
Dose 1: Day 0
Dose 2: Day 7
This provides faster protection for last-minute travellers.
A booster may be considered if you continue to travel to JE-endemic regions.
Vaccination is recommended for travellers who:
Are staying long-term in rural or agricultural regions
Will be doing outdoor activities (camping, trekking, cycling)
Will be travelling during the rainy season
Are visiting rural families or staying in local homes
Are undertaking fieldwork or adventure travel
Are travelling to regions with ongoing JE transmission
Are laboratory workers exposed to JE virus
Short-term urban travellers generally have a very low risk, but vaccination can be considered depending on itinerary.
Northfields Travel Clinic provides the JE vaccine on-site at Bramley Pharmacy, 261 Northfield Avenue, Ealing (W5).
Use our online booking widget to schedule your 2-dose course or accelerated schedule.
Protect yourself, reduce your risk of severe neurological illness, and travel with confidence.
No — it is rare, especially in short-term urban travellers. Risk increases with rural night-time exposure.
Yes — Ixiaro® is licensed from 2 months of age.
For most travellers, the standard Day 0 & Day 28 schedule is used.
If leaving soon, adults 18–65 can use the Day 0 & Day 7 accelerated option.
Yes — JE vaccine does not prevent other mosquito-borne diseases.
1–2 years initially. A booster is recommended if you travel again to high-risk areas.
Yes. Ixiaro® is an inactivated vaccine and has an excellent safety record.
NaTHNaC / TravelHealthPro – Japanese Encephalitis
https://travelhealthpro.org.uk/factsheet/31/japanese-encephalitis
WHO – JE Factsheet
https://www.who.int/news-room/fact-sheets/detail/japanese-encephalitis
ECDC – Japanese Encephalitis Overview
https://www.ecdc.europa.eu/en/japanese-encephalitis